WebJun 1, 2015 · The chromosome transmission fidelity (CTF) assay measures whole chromosome loss by using an artificial chromosome. The a-like faker (ALF) assay uses a readout that can be the consequence of a whole chromosome loss, chromosome rearrangements, or gene conversion. ... Miltenyi Biotec) to count the number of green … WebFeb 9, 2004 · The Ndc80 complex consists of four essential proteins: Ndc80p, Nuf2p, Spc24p, and Spc25p. Among these, Ndc80p and Nuf2p are well conserved among eukaryotes ( Wigge and Kilmartin, 2001) and human Ndc80 (Hec1) can functionally substitute for its yeast counterpart ( Zheng et al., 1999 ).
CHTF8 - Chromosome transmission fidelity protein 8 …
WebAn alternative clamp loader complex termed chromosome transmission fidelity protein 18 and replication factor C (CTF18‑RFC) has been shown to act as a positive regulator of two types of replication stress response: S‑phase checkpoint signaling and … WebJun 10, 2013 · Homozygous ctf7-1 male meiocytes are defective in chromosome pairing and segregation. 4′,6-Diamidino-2-phenylindole stained male meiocytes from ctf7-1 plants are shown. A number of alterations are observed. (a) Pre-leptotene. Chromosomes of ctf7-1 failed to distribute in the nuclear periphery. (b) Leptotene. irish toy stores
Regulation of PCNA–protein interactions for genome stability
WebFeb 6, 2024 · Here, based on characterization of a dwarf rice (Oryza sativa) mutant (dwarf-related wd40 protein 1, drw1) deficient for yeast CTF4 (CHROMOSOME TRANSMISSION FIDELITY PROTEIN 4), we discovered... WebMar 21, 2024 · CHTF18 (Chromosome Transmission Fidelity Factor 18) is a Protein Coding gene. Diseases associated with CHTF18 include Roberts-Sc Phocomelia … WebThe CTF18-RFC complex catalyzes the ATP-dependent loading of PCNA onto primed and gapped DNA. It also interacts with and stimulates POLH, which is suggestive of a protein network that coordinates DNA repair, recombination and chromosome cohesion reactions with replication fork progression. irish toy show