Cisplatin cardiomyopathy

Author: tcyp

August undefined, 2024

WebMar 17, 2024 · Cardiotoxicity is defined as any heart injury (functional or structural) related to cancer treatment, taking into consideration chemotherapy, radiotherapy … WebJun 1, 2013 · Cardiotoxicity is a well known consequence of cancer chemotherapy. Cisplatin-based combinations are standard regimens in the therapy of advanced non-small cell lung cancer. Administration of cisplatin-containing chemotherapy causes significant oxidative and nitrosative stress in some patients.

Cisplatin and Congestive cardiomyopathy, a phase IV clinical …

WebMar 12, 2015 · We previously demonstrated that the increase in troponin I (TnI) soon after high-dose chemotherapy (HDC) is a strong predictor of left ventricular dysfunction and poor cardiac outcome, particularly in patients showing a persistent TnI increase. 5,6 This finding has important clinical implications and allows the identification of patients at high risk of … WebAug 1, 2012 · Traditional and novel chemotherapy agents can damage the heart or peripheral blood vessels, or cause problems with clotting or blood lipids. Some … on site fall protection training

Cisplatin nephrotoxicity as a model of chronic kidney disease

WebApr 2, 2024 · Cardiomyopathy (kahr-dee-o-my-OP-uh-thee) is a disease of the heart muscle that makes it harder for the heart to pump blood to the rest of the body. Cardiomyopathy can lead to heart failure. The main types … WebNational Center for Biotechnology Information WebCisplatin-induced cardiotoxicity is a well describe effect with a low incidence. Supraventricular arrhythmias and coro-nary artery disease are the main cardiac effects. ... Cardiotoxicity secondary to cisplatin administration manifests as both delayed effects (mainly as chronic ischemic cardiomyopathy and arterial hypertension) and acute ... ioc 容器和dependency injection 模式

Cardiotoxicity of chemotherapeutic agents: incidence, treatment and ...

Cardiovascular Complications of Cancer Therapy

WebJan 10, 2011 · Cisplatin-induced cardiotoxicity: Mechanisms and cardioprotective strategies. Increased oxidative stress and apoptosis have been implicated in the cardiotoxicity that … WebApr 11, 2024 · The package insert for Adriamycin states that lifetime cumulative doses above 550 mg/m2 (21-day cycles) are associated with an increased risk of cardiomyopathy. In people at higher risk of cardiotoxicity, the maximum cumulative dose of doxorubicin should be limited to less than 400. on site fencing vernon bcWebApr 21, 2024 · If you’re receiving carboplatin or cisplatin chemotherapy, talk to your doctor about the risks to your hearing. Heart problems Chemotherapy can lead to high blood … on site fire extinguisher training

"WebNov 17, 2024 · joint or muscle pain. loss of appetite. lower back or side pain. muscle tremors. nausea or vomiting. rapid, deep breathing. red, irritated eyes. red skin lesions, often with a purple center. restlessness. " - Cisplatin cardiomyopathy

Cisplatin cardiomyopathy

Cisplatin based therapy: the role of the mitogen activated protein ...

WebOct 11, 2024 · Weakening of the heart muscle (cardiomyopathy) Heart rhythm problems (arrhythmia) Heart attack Stroke High blood pressure Blood clots Whether you're at risk … WebMay 4, 2024 · Signs and symptoms of dilated cardiomyopathy may include: Fatigue. Shortness of breath (dyspnea) during activity or while lying down. Reduced ability to exercise. Swelling (edema) in the legs, ankles, …

Did you know?

WebJan 1, 2013 · Patients receiving cisplatin-based chemotherapy may experience coronary artery diseases, arrhythmias, and cardiomyopathy 3). Moore et al. have reported cases of arterial thrombosis with subsequent ... WebFeb 2, 2024 · Learn about the potential side effects of pemetrexed. Includes common and rare side effects information for consumers and healthcare professionals.

WebChemotherapeutic drugs can cause cardiac toxicities such as cardiomyopathy, arrhythmia, and cardiovascular disease. The well-known side effects of cisplatin are nephrotoxicity, nausea, vomiting, and electrolyte imbalance. Cardiotoxicity induced by cisplatin is rare, and its pathophysiology is unknown. WebCardiotoxicity has been well documented as a side effect of cisplatin (CDDP) treatment. The inflammatory response plays a crucial role in the pathological process of CDDP-induced cardiotoxicity. Wogonin is a natural flavonoid compound that possesses cardioprotective and anti-inflammatory qualities.

WebOct 1, 2013 · Chemotherapy may induce entire spectrum of cardiac pathology. Cisplatin (CDDP) is a widely used chemotherapeutic agent and its use is limited by its wide range of toxicities, most common being renal and neurotoxicity. Cardiotoxicity of cisplatin is less common and may range from silent and symptomatic arrhythmias to cardiomyopathy … WebAcute clinical syndromes associated with cisplatin infusion include chest pain, palpitations, and, occasionally, elevated cardiac enzymes indicative of myocardial infarction (MI). 16 …

WebOct 6, 2024 · The following are common signs of cardiomyopathy: Trouble breathing when you’re active or resting. Some people might also need to sleep sitting up or with many pillows under their head to help them …

WebSummary: Congestive cardiomyopathy is found among people who take Cisplatin, especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months. The phase IV clinical study analyzes which people take Cisplatin and have Congestive cardiomyopathy. It is created by eHealthMe based on reports of 79,691 people who … iod 10 maps no bluetoothWebNational Center for Biotechnology Information ioc yugioh setWebJul 23, 2024 · Clinical implication of Cisplatin (cis-dichlorodiammine-platinum (II), CP) is restricted owing to augmented oxidative stress and apoptosis that have been involved in cardiac injury. Cisplatin usage is also associated with the cardiotoxicity including arrhythmia, myocarditis, cardiomyopathy and congestive heart failure [1,2,3,4,5]. onsite fire extinguisher trainingWebJun 1, 2013 · Cisplatin-based combinations are standard regimens in the treatment of advanced non-small cell lung cancer, significantly improving survival of patients. … ioc young reportersWebThis study has been initiated to investigate whether endogenous carnitine depletion and/or carnitine deficiency is a risk factor during development of cisplatin (CDDP)-induced cardiomyopathy and if so, whether carnitine supplementation by propionyl-L-carnitine (PLC) could offer protection against this toxicity. on site fire marshall trainingWebApr 11, 2024 · Cisplatin is a widely used chemotherapeutic agent for treatment of various cancers. However, treatment with cisplatin is associated with drug resistance and several adverse side effects such as nephrotoxicity, reduced immunity towards infections and … iod-09thWebCisplatin can induce direct myocardial toxicity leading to atrial fibrillation whereas the potential of myocardial toxicity is amplified when the drug is administered in … ioc welding supply