WebContraindications to the use of the triptans include coronary artery disease, a history of stroke, peripheral vascular disease and chronically uncontrolled high blood pressure. Triptans are considered category C in pregnancy, so the risks and benefits must be weighed for each patient. WebThe serotonin (5-hydroxytryptamine [5-HT]) receptor subtype 1 B /1 D agonists, called triptans, are nowadays the first-line acute therapy for patients who experience moderate-to-severe migraine attacks. Unfortunately, a high percentage of patients are not satisfied with this acute treatment, either for lack of response or side effects.
The safety of triptans in the treatment of patients with
WebAug 18, 2024 · Several mechanisms have been shown or suspected, such as endothelial dysfunction, alteration of coagulation or fibrinolysis, or promotion of vascular risk factors. 1, 2 Some drugs are also known to induce heart diseases such as dilated cardiomyopathy 3 or atrial fibrillation, 4 leading to cardiogenic emboli. WebBackground: The use of triptans (5-HT agonists) in the treatment of migraine is associated with a potential increasing risk of cardiovascular events and raises the question of the relationship between overuse and the occurrence of ischemic events. list of camp activities
Triptans in migraine: the risks of stroke, cardiovascular …
WebOct 1, 2013 · Hospitalized stroke patients: Hospitalized and nonhospitalized patients with SAH: Controls: ... History of migraine and risk of cerebral ischaemia in young adults. The Italian National Research Council Study Group on Stroke in the Young. ... Triptans in migraine: the risks of stroke, cardiovascular disease, and death in practice. Neurology ... WebDec 15, 2024 · The findings, published in JAMA Network Open, “may imply that triptans will remain the current mainstay of specific acute migraine ... and ubrogepant (both calcitonin gene-related peptide [CGRP] antagonists) might still have unique advantages, since triptans are contraindicated for patients with cardiovascular risks, they said. The systemic ... images of the bold and the beautiful